Occasionally there are PC hardware updates that impact tools within Powermill. Your Graphics card drivers can cause issues if a driver update resets the use settings of your card. With Powermill it is common that these settings cause the setup utilities to stop working. To fix this issue follow the link below with instructions from the Autodesk knowledge network to reset your Nvidia card to the necessary settings. 


https://knowledge.autodesk.com/support/powermill/troubleshooting/caas/sfdcarticles/sfdcarticles/A-blank-snapshot-image-is-displayed-while-creating-a-setup-sheet-in-PowerMill.html